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ivive.app

app.ivive/iviveVersion 1.0.3

Human hepatic clearance from in-vitro CLint, with the error band measured on known drugs.

Status

Responds142 msAnswered our handshake without sign-in.

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Last checked
Nov 14, 2026, 13:36 UTC
Latency
142 ms
Remotes responding
1 of 1
Sign-in
No sign-in
Hosting
EU hosting detected (detected, not a legal statement)
Registry data as of
Nov 14, 2026, 22:14 UTC

Data from the official MCP Registry, checked by run.zero. How we check

Connect

Streamable HTTP
https://api.ivive.app/mcp/Responds142 ms
No sign-in

Claude Code

claude mcp add --transport http ivive https://api.ivive.app/mcp/

Claude Desktop and claude.ai

Settings > Connectors > Add custom connector
Name: ivive
Remote MCP server URL: https://api.ivive.app/mcp/

Cursor

{
  "mcpServers": {
    "ivive": {
      "url": "https://api.ivive.app/mcp/"
    }
  }
}

VS Code

code --add-mcp '{"name":"ivive","type":"http","url":"https://api.ivive.app/mcp/"}'

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Tools

6 tools

Tools of ivive.app
Read-only
Idempotent
Open world
calc_clhepHepatic and plasma clearance from in-vitro CLint, fu,mic and fu,p (IVIVE), with the observed-CL band and applicability warnings. If fu,p or fu,mic came from predict_inputs, tell the user the result rests on predicted inputs.NoYesYesNo
input_sensitivityHow far plasma CL moves as each input is varied over a range, e.g. a predicted fu,p over its 50% range.NoYesYesNo
predict_inputsPredict fu,p and fu,inc from a SMILES, with structure-only human CL and Vss as second opinions. Predictions, not measurements; check the applicability verdict.NoYesYesNo
scale_to_humanPredict human plasma CL from observed animal in-vivo CL (rat, dog, monkey), every applicable method with its measured error. Observed animal CL only, never predicted.NoYesYesNo
similar_drugsNearest reference drugs to a SMILES (Tanimoto, Morgan radius 2), each with measured human plasma CL and the CL IVIVE predicted from its measured inputs. Use it to judge how far to trust calc_clhep for this chemotype: if IVIVE missed on the neighbours, expect it to miss here. Returns neighbours only, not a prediction for the query.NoYesYesNo
target_clintThe in-vitro CLint an assay must read for a compound to reach a target plasma clearance (mL/min/kg): calc_clhep run backwards, e.g. to set a CLint cut-off for a screening cascade. Needs fu,mic and fu,p; refuses a target at or above the liver blood flow ceiling and returns that ceiling. Uncorrected IVIVE, so no error band.NoYesYesNo

Details

Registry status
Active
Published
Oct 29, 2026
Updated
Oct 29, 2026
Repository
Not given
Categories
Uncategorized
GDPR
Not declared

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